Josei manga are Japanese comics aimed at older teenage girls and adult women who are able to read kanji without the aid of furigana. Josei manga should not.
I found The Life-Changing Manga of Tidying Up, by Marie Kondo, at the library today Takes the perspective of an adult female protagonist;.
Here are the list of Josei (older female manga) that deal with mature theme, such as adult relationships, work, and life. Plus they have pretty art.